In Brief:
7/30/2010 Print E-mail Contrave, an experimental weight loss drug that combines an antidepressant with an anti-addiction medication, appears to help users shed pounds when taken along with a healthy diet and exercise, researchers report.. The drug, which is up for U.S. Food and Drug Administration review this December, appears to boost weight loss by changing the workings of the body's central nervous system, the researchers report.. However, about 30 percent of those taking Contrave experienced nausea, the study authors say, and other side effects included headache, constipation, dizziness, vomiting and dry mouth.. Still, Contrave may give people struggling to lose weight a new option, the researchers contend. This may have been due to side effects of medications, the fact that it is hard to stick to dietary changes for 56 weeks, or [the fact that] slow and only modest weight loss did not meet participant expectations.
